Ongoing studies
At St.Claraspital we practice a patient-oriented research directly on and with the patient or test person. This practice includes clinical studies, but also epidemiological studies and case-control studies. Below is the study list of the current open oncological, haematological and metabolic studies.
Oncological studies
| Breast | |||
|---|---|---|---|
| Elasto Trial | Comparison of accuracy and reproducibility of breast lesion characterization between real time elastography and shear wave elastography. Learn more | R. Zanetti Dällenbach | R. Zanetti Dällenbach |
| SAKK 23/16 (TAXIS) | Tailored axillary surgery with or without axillary lymph node dissection followed by radiotherapy in patients with high risk node-positive breast cancer: A multicenter randomized open labeled phase III trial (TAXIS) | R. Zanetti Dällenbach | Ch. Riggenbach |
| Colon | |||
|---|---|---|---|
| PREVASCO trial | Biomarker at CRC: Prospective sample collection for the evaluation of next generation colorectal cancer screening blood test, Colox®, for the detection of advanced adenoma and colorectal cancer. | B. Wölnerhanssen | G. Reinhard, A. Etter-Atlass, V. Pflimlin-Fritschy |
| SAKK 41/13 | Adjuvant aspirin treatment in PIK3CA mutated colon cancer patients. A randomized, double-blinded, placebo-controlled, phase III trial adjuvant Learn more | D. Köberle | C. Riggenbach |
| SAKK 41/16 | Neoadjuvant treatment with Regorafenib and Capecitabine combined with radiotherapy in locally advanced rectal cancer. A multicenter phase Ib trial (RECAP). Learn more | D. Köberle | C. Riggenbach, G. Reinhard |
| Cancer diagnostics | Principal Investigator | Coordinator | |
|---|---|---|---|
| 4D_Liquid-Biopsies | Prospective Evaluation of 4D LifetestTM Parameters to Develop a Universal Early Cancer Diagnosis Test | B. Wölnerhanssen | A. Etter-Atlass, V. Pflimlin-Fritschy |
| Lungs | Principal Investigator | Coordinator | |
|---|---|---|---|
| SAKK 16/18 | Immune modulatory radiotherapy to enhance the effects of neoadjuvant PD L1 blockade after neoadjuvant chemotherapy in patients with resectable stage III(N2) non small cell lung cancer (NSCLC). A multicenter phase II trial. | M. Buess | G. Reinhard |
| Lymphoma | Principal Investigator | Coordinator | |
|---|---|---|---|
| SAKK 35/14 | Rituximab with or without Ibrutinib for untreated patients with advanced follicular lymphoma in need of therapy. A randomized, double-blinded, SAKK and NLG collaborative phase II trial. Learn more | M. Ebnöther | C. Riggenbach |
| Palliative Care | Principal Investigator | Coordinator | |
|---|---|---|---|
| SAKK 96/12 (Palliative care) | Prevention of Symptomatic Skeletal Events with Denosumab Administered Every 4 weeks versus every 12 Weeks – A Non-Inferiority Phase III Trial | A. Templeton | C. Riggenbach |
| Pancreas | Principal SAKK 44/19 | ||
|---|---|---|---|
| SAKK 44/19 | Irreversible electroporation (IRE) followed by | M. Bolli | U. Heisner |
| Prostate | Principal Investigator | Coordinator | |
|---|---|---|---|
| BEDNA-Study | Blood collection for the analysis of cell-free DNA in patients with advanced cancer | T. Zellweger | G. Reinhard |
| Ex Vivo | Fresh tissue ex-vivo: development of ex vivo models of prostate cancer | T. Zellweger | G. Reinhard |
| PCO-CRV | Prostate Cancer Outcomes – Compare & Reduce Variation in Prostate Cancer Centers certified by the German Cancer Society | T. Zellweger | G. Reinhard |
| Testicles | Principal Investigator | Coordinator | |
|---|---|---|---|
| SAG TCCS | Prospective data collection in patients with testicular cancer | A. Templeton | C.Riggenbach |
| Registry / observation studies | Principal Investigator | Coordinator | |
|---|---|---|---|
| SAKK 80/20 (COVID-19) | The SAKK 80/20 study aims to find out what effect a COVID-19 illness has on cancer patients. | D. Köberle | C. Riggenbach |
| SAKK 80/19 Alpine TIR | Alpine Tumor Immunology Registry | T. Schmid | C. Riggenbach |
Metabolic Studies
Bariatric surgery
| Oesophagus | Principal Investigator | Coordinator | |
|---|---|---|---|
| FUB A & B | Long-term adverse effects after laparoscopic sleeve gastrectomy and Roux-Y-Gastric Bypass: Part A Bone and Part B Oesophagus Learn more | B.Wölnerhanssen, AC. Meyer-Gerspach | U. Ruscher, A. Etter-Atlass |
| Taste physiology | Principal Investigator | Coordinator | |
|---|---|---|---|
| Taste 2 | Taste physiology in morbidly obese patients before and after bariatric surgery. Learn more | B.Wölnerhanssen, AC. Meyer-Gerspach | A. Etter-Atlass |
Natural Sweeteners
| Gut microbiota: Xylitol/Erythritol | Principal Investigator | Coordinator | |
|---|---|---|---|
| PolyGut | Effect of the natural sweeteners erythritol and xylitol on gut microbiota and glucose metabolism in obese volunteers: a pilot study Learn more | B.Wölnerhanssen, AC. Meyer-Gerspach | A. Etter-Atlass |
| Sweet receptors: D-Allulose/Erythritol | Principal Investigator | Coordinator | |
|---|---|---|---|
| PolyAlluLac | Acute effects of the two alternative sweeteners D-allulose and erythritol on gastrointestinal hormone secretion and glycemic control Learn more | A.C. Meyer-Gerspach | A.Etter-Atlass |
| Vascular function: Xylitol/Erythritol | Principal Investigator | Coordinator | |
|---|---|---|---|
| PolyVasc | Effect of the natural sweeteners erythritol and xylitol on vascular function in obese volunteers: a pilot study Learn more | B.Wölnerhanssen, AC. Meyer-Gerspach | A. Etter-Atlass |
Nutrition
| Low Carb Program | Principal Investigator | Coordinator | |
|---|---|---|---|
| LCP Sinergia | Understanding gut-brain interactions and the effect of a low crab dietary intervention in obese patients with daibetes or glucose intoleance: a pilot trial. Learn more | B. Wölnerhanssen | A. Etter-Atlass, V. Bordier |
Contact Clara Research
St. Clara Forschung AG
Kleinriehenstr. 43
4058 Basel
Tel.: 061 685 85 85
forschung@claraspital.ch
Contact Clara Hospital
Our business hours run from Monday to Friday 8 am to 5 pm. Outside the phone times our reception is manned around the clock.
Reception
T: 061 685 85 85
