BASEC 2020-00148
Maintenance therapy with an aromatase inhibitor for epithelial ovarian cancer
Research provides scientifically proven answers to medical questions and thus contributes to the improvement of medical care.
Clinical studies are conducted directly on and with the patient. This can be very different. For example, by testing the effect or dosage of a drug or by comparing different treatment methods for an indication. Numerous studies are currently being conducted at St. Clara Forschung AG:
Current studies
Abdominal wall/groin
BASEC 2021-01655
The aim of this study is to investigate whether robotic inguinal hernia repair can reduce postoperative pain and improve recovery compared to the conventional laparoscopic approach.
Current studies
Pancreas (pancreas)
BASEC 2023-00705
Partial removal of the pancreas - comparison of the keyhole technique and open surgery.
Current studies
Breast (mamma)
BASEC 2019-01493
This study is investigating whether certain biological markers or parameters measured by the 4D Lifetest™ can be used to detect cancer at an early stage, before symptoms appear. The aim is to create a reliable and broad test that can be used for different types of cancer.
BASEC 2020-02830
A study at several clinics is investigating various surgical methods to check the armpits of breast cancer patients with affected lymph nodes. These patients receive chemotherapy before surgery. The aim of the study is to compare the best surgical procedures.
BASEC 2023-00646
An observational, non-interventional, multi-site study to evaluate different imaging techniques for the accurate detection of malignant breast tumours.
KEK-ZH-No. 2014-0109
Skeletal metastases in breast and prostate cancer. Prevention of symptomatic skeletal complications with denosumab administered every 4 weeks versus every 12 weeks.
BASEC 2020-00450
The study is investigating whether an intelligent, vacuum-assisted biopsy can be used directly before surgery for breast cancer in order to recognise how well patients have responded to previous chemotherapy before or during the operation.
Current studies
Intestine
BASEC 2022-00899
Cholecalciferol co-medication in patients with chronic inflammatory bowel disease (Crohn's disease or ulcerative colitis)
BASEC 2020-03069
Comparison and measurement of health-related quality of life in patients with colorectal cancer.
BASEC 2022-02297
Snapshot Audit on Early onset Colorectal Cancer - are we doing enough, can we do more?
BASEC 2019-01441
To further investigate the clinical significance of tumour cell characteristics in colorectal cancer. This is done by establishing a platform for analysing the genetic profile and the effect of cancer drugs in patients with colorectal cancer.
BASEC 2022-00647
This study is investigating the efficacy of the combination of Braftovi capsules (active ingredient encorafenib) and Erbitux or an equivalent drug (biosimilar) (active ingredient cetuximab) in metastatic colorectal cancer. The data obtained in this study should help to gather experience with these approved drugs under routine conditions.
BASEC 2022-02161
An observational study on quality of life in newly diagnosed anal carcinoma
BASEC 2019-01199
Identification of biomarkers to predict response to pre-treatment in rectal cancer
Current studies
Ovaries
Current studies
Nutrition/overweight
BASEC 2019-02109
The importance of the gut-brain axis and the effect of a low-carbohydrate diet on obesity and depression
Current studies
Testicles
EKOS 13/083, PB_2016-00235
Prospective data collection in patients with testicular cancer
Current studies
Lung
BASEC 2019-01493
This study is investigating whether certain biological markers or parameters measured by the 4D Lifetest™ can be used to detect cancer at an early stage, before symptoms appear. The aim is to create a reliable and broad test that can be used for different types of cancer.
BASEC 2023-00398
It is a database that collects information on patients with a specific type of lung cancer (metastatic non-small cell lung cancer, NSCLC). The aim is to better understand how these genetic changes affect the course of the disease and treatment outcomes.
BASEC 2019-02378, EKOS 19/185
The SAKK 16/18 trial is investigating whether additional preoperative immunotherapy with the anti-PD-L1 antibody durvalumab in combination with radiotherapy can improve the prognosis of locally advanced non-small cell lung cancer (NSCLC).
BASEC 2022-00738
New tools to improve the treatment of patients with suspected pneumonia
BASEC 2019-01150
The DANTE/FLOT8 study is investigating whether a combination of two treatments for gastric cancer and adenocarcinoma at the junction between the oesophagus and stomach works better than one of the treatments alone.
BASEC 2017-01217
The registry will collect data from patients receiving immunotherapy. The type of immunotherapy, tumour type, tumour response tumour response overall disease control rate), overall survival, all lines of therapy therapy before and after the specified line of treatment, laboratory values laboratory values and the results reported by the patients will be documented.
Current studies
Blood and lymphatic system
KEK-BE: 339/2014; PB_2016-01917
Data and sample collection to identify new biological correlations in myeloplastic syndrome, which also allow a description of the current status and future developments in diagnostics and therapy.
Current studies
Stomach and oesophagus
BASEC 2019-02118
Molecular investigations of abdominal tumours using in-vivo and in-vitro test methods.
BASEC 2023-00126
Comparison of surgical therapies for adenocarcinoma of the gastro-oesophageal junction (GEJ): transthoracic oesophagectomy versus transhiatal extended gastrectomy.
Current studies
Testicles
EKOS 13/083, PB_2016-00235
Prospective data collection in patients with testicular cancer
Current studies
Kidney
BASEC 2018-01473
A project being carried out at several centres is investigating factors that predict the course of the disease and influence treatment success in modern therapy.
BASEC 2017-01217
The registry will collect data from patients receiving immunotherapy. The type of immunotherapy, tumour type, tumour response tumour response overall disease control rate), overall survival, all lines of therapy therapy before and after the specified line of treatment, laboratory values laboratory values and the results reported by the patients will be documented.
Current studies
Prostate
EKNZ 2014-329
Analysis of freely circulating genetic substances from cancer cells in the blood of patients with advanced cancer. The establishment of this technology could enable the treatment and monitoring of advanced cancer in the future.
EKBB 37/13, PB_2018-00312
The identification of specific mutations could improve the basic understanding of the development of prostate cancer, especially castration-resistant prostate cancer, and help to develop new markers and strategies for its treatment.
BASEC 2016-01172
International comparison of treatment and outcome quality for localised prostate cancer
BASEC 2021-02495
The aim is to find out whether it is possible to identify at an early stage which therapy will work particularly well by examining tumour DNA in prostate cancer patients. This would enable doctors to offer more individualised, more effective treatments that are better suited to the patient's particular type of cancer than the usual standard treatments.
KEK-ZH-No. 2014-0109
Skeletal metastases in breast and prostate cancer. Prevention of symptomatic skeletal complications with denosumab administered every 4 weeks versus every 12 weeks
Current studies
Other
BASEC 2019-02118
Molecular investigations of abdominal tumours using in-vivo and in-vitro test methods.
KEK-BE 395/2014
Data is collected from patients with NET from all over Switzerland. Based on this data, the frequency and course of these rare tumours in Switzerland can be better documented. Interested specialists from the various specialities are united in the sponsoring association of this registry, which also leads to a lively exchange of knowledge.